Abstract Concurrent amplifications of EGFR and PDGFRA have been reported in up to 5% of glioblastoma (GBM) and it remains unclear why such independent amplification events, and associated receptor overexpression, would be adaptive during glioma evolution.Here, we document that EGFR and PDGFRA protein co-expression occurs in 37% of GBM.There is wide
Water is crucial for socio-economic development and healthy Ski de fond - Homme - Vetements - Pantalon ecosystems.With the actual population growth and in view of future water scarcity, development calls for improved sectorial allocation of groundwater and surface water for domestic, agricultural and industrial use.Instead of intensifying the press
Abstract The existence of effective therapies for most cardiovascular disease states, coupled with increased requirements that potential benefits of new drugs be evaluated on clinical rather than surrogate endpoints, makes it increasingly difficult to substantiate any incremental improvements in efficacy that these new drugs might offer.Compounding
Sustained growth of world-wide sea farming and the search of optimal growing conditions have driven several countries, including Norway, to establish new finfish sites in more exposed, high current locations.Characterized by a range of gravel, broken rock and/or bedrock, these complex environments and the associated diverse range of epifauna specie
The characteristics of magnetohydrodynamics hybrid nanofluid flow in an irregular wall are explored theoretically.Since the movement of nanoparticles significantly impacts the flow, the Brownian motion and thermophoresis effect are incorporated in this investigation.The flow model is formulated through the non-dimensionalized nonlinear partial diff